• Users Online: 658
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2016  |  Volume : 11  |  Issue : 2  |  Page : 41-43

Bilateral optic neuritis as the presenting symptom of multiple sclerosis


1 Department of Neurology, Isfahan Neuroscience Research Center, Isfahan, Iran
2 Department of Ophthalmology, Isfahan Eye Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Correspondence Address:
Seyed Ali Sonbolestan
Department of Ophthalmology, Isfahan University of Medical Sciences, Isfahan
Iran
Login to access the Email id


DOI: 10.4103/1858-5000.185229

Rights and Permissions

Background: Optic neuritis (ON) is one of the earliest manifestations of multiple sclerosis (MS). The prevalence of bilateral ON (BON) as the presenting symptom is not clear. The aim of this study was to evaluate the prevalence of BON as the presenting symptom in MS and compare it with unilateral ON (UON). Subjects and Methods: In this study, two groups of definite MS patients according to the McDonald's criteria were enrolled: Thirty patients with BON and fifty persons with UON (selected randomly from all of the UON patients) as the presenting manifestation. The patients' data were collected from the Isfahan MS Society Registry. The SPSS 22 software was used for analysis of the data. P <0.05 considered as significant. Results: Thirty of 3972 MS patients presented with BON. The mean of their ages was 26.00 ± 6.29 in BON and 30.10 ± 8.25 in UON group (P = 0.015). Twenty-five of BON patients were females, and five were males and in the UON group, 42 were females, and eight were males. Expanded disability status scale was 1.83 ± 1.17 in BON and 1.84 ± 1.25 in UON group (P = 0.975). The severities of relative afferent pupillary defect (RAPD) (in pluses) were 2.00 ± 0.52 and 1.43 ± 0.72 in two groups, respectively. Conclusions: The prevalence of BON as the presenting symptom was about 0.7%. The patients who presented with BON were younger at the time of diagnosis when they were compared with those who diagnosed with UON and also had a more severe RAPD. BON could be considered as one of the important presenting manifestations of MS.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1355    
    Printed45    
    Emailed0    
    PDF Downloaded139    
    Comments [Add]    

Recommend this journal